强直性脊柱炎其实是生活中的多发疾病，所以大家应该都有所听说过，而且该疾病的对人体的危害也是非常大的。据了解，知道强直性脊柱炎的人很多，但是却没有几个人对该疾病是了解的。所以今天为大家介绍的内容就是关于强直性脊柱炎的定义是什么，希望能够增强人们对该疾病的了解。请看具体内容介绍：
\n强直性脊柱炎的定义
\n强直性脊柱炎(ankylosing spondylitis，as)是一种主要侵犯脊柱，并累及骶髂关节和周围关节的慢性进行性炎性疾病。本病又名marie-strümpell病、von bechterew病、类风湿性脊柱炎、类风湿中心型等，现称as。由于本病也可侵犯外周关节，并在临床、放射线和病理表现方面与ra相似，故长时间以来一直被看成是类风湿关节炎的一种变异型，称为类风湿性脊柱炎。
\n症状体征
\n这类疾病以肌腱端炎、指/趾炎或少关节炎起病，部分病例可发展成骶髂关节炎和脊柱炎，伴有或不伴有急性前葡萄膜炎或皮肤黏膜损害等关节外表现。肌腱端部位受到淋巴细胞、浆细胞和多形核白细胞浸润，其附近的骨髓腔也出现水肿和受到浸润。强直性脊柱炎的显著特点是，其中轴肌端炎和滑膜炎的高发生率，且最终导致骶髂关节和脊柱的纤维化和晚期的骨性强直。
\n虽然所有强直性脊柱炎患者均有不同程度的骶髂关节受累，临床上真正出现脊柱完全融合者并不多见。骶髂关节炎引起的炎性腰痛，呈隐匿性、很难定位，并感到臀部深处疼痛。起病初，疼痛往往是单侧和间歇性的，几个月后逐渐变成双侧和持续性，并且下腰椎部位也出现疼痛。典型的症状是固定某一姿势的时间较长或早晨醒来时症状加重(“晨僵”)，而躯体活动或热水浴可改善症状。
\n男女发病之比为7∶1～10∶1。起病多为15～30岁的男性，儿童及40岁以上者少见。强直性脊柱炎一直被认为是主要见于男性的疾病，现在研究提示，该病男女之比为2∶1～3∶1。对男女强直性脊柱炎患病率的差异至今尚乏满意的解释。职业、妊娠对本病均无大影响，而性激素的作用亦尚不肯定。
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强直性脊柱炎是较复杂的一种疾病了，生活中会有很多的朋友出现该病的症状，因此会给患者的关节健康带来了伤害，各位朋友需要将强直性脊柱炎关注起来，特别是要将此病的危害了解透彻，往下看认识一下相关的危害有哪些呢。
\n强直性脊柱炎的危害：
\n活动受限，大部分强直性脊柱炎患者首先出现腰骶部或腰部疼痛，常伴有僵硬感，呈间接性和反复发作，影响腰部活动。随病情的发展，可导致腰部肌肉萎缩，伴有肌力减退、腱反射较弱或消失，致使患者活动进一步受限，严重时生活不能自理甚至卧床。骨质疏松，强直性脊柱炎患者普遍都伴有骨质疏松，以椎体改变比较明显，并且多伴有骨质增生、韧带骨化和骨关节硬化等，一般常常是骨质增生和骨质疏松同时并存，以脊柱各椎体表现最为明显。强直性脊柱炎晚期有少数患者马尾神经受损出现慢性进行性马尾神经综合征。
\n眼损害，眼损害也是患上强直性脊柱炎疾病的危害之一，是最常见的关节外表现，以急性葡萄膜炎和急性虹膜炎多见，也可发生急性结膜炎，如治疗不当或延误治疗，也可发生视力障碍。肩关节，强直性脊柱炎也会导致肩关节强直。肩关节活动受限主要来源于肿胀，它会影响患者梳头、抬手等日常活动。
\n髋关节强直，强直性脊柱炎对髋关节的影响是最为普遍的。临床调查发现：髋关节强直的患者共占强直性脊柱炎中晚期的60%以上。髋部疼痛剧烈，其部分表现为臀部、腹股沟部位、大腿内侧部位疼痛，继续发展髋关节活动功能受限，髋关节周围肌肉萎缩，最后髋关节出现骨性强直。心脏病变，强直性脊柱炎的危害不仅体现在对患者情绪的影响，还会造成患者的心脏病变。以主动脉瓣病变较为常见，据尸检发同约25%的强直性脊柱炎病例中，有主动脉根部病变，心脏受累在临床上可无症状，亦可有明显表现。
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目前强直性脊柱炎的危害十分严重，会有很多的朋友在生活当中出现此病的症状，因此会给患者带来困扰，我们要将强直性脊柱炎了解透彻，应当将此病带来的危害了解清楚才行，往下看为大家介绍一下强直性脊柱炎的危害有哪些。
\n强直性脊柱炎的危害：
\n活动受限，大部分强直性脊柱炎患者首先出现腰骶部或腰部疼痛，常伴有僵硬感，呈间接性和反复发作，影响腰部活动。随病情的发展，可导致腰部肌肉萎缩，伴有肌力减退、腱反射较弱或消失，致使患者活动进一步受限，严重时生活不能自理甚至卧床。骨质疏松，强直性脊柱炎患者普遍都伴有骨质疏松，以椎体改变比较明显，并且多伴有骨质增生、韧带骨化和骨关节硬化等，一般常常是骨质增生和骨质疏松同时并存，以脊柱各椎体表现最为明显。强直性脊柱炎晚期有少数患者马尾神经受损出现慢性进行性马尾神经综合征。
\n眼损害，眼损害也是患上强直性脊柱炎疾病的危害之一，是最常见的关节外表现，以急性葡萄膜炎和急性虹膜炎多见，也可发生急性结膜炎，如治疗不当或延误治疗，也可发生视力障碍。肩关节，强直性脊柱炎也会导致肩关节强直。肩关节活动受限主要来源于肿胀，它会影响患者梳头、抬手等日常活动。
\n髋关节强直，强直性脊柱炎对髋关节的影响是最为普遍的。临床调查发现：髋关节强直的患者共占强直性脊柱炎中晚期的60%以上。髋部疼痛剧烈，其部分表现为臀部、腹股沟部位、大腿内侧部位疼痛，继续发展髋关节活动功能受限，髋关节周围肌肉萎缩，最后髋关节出现骨性强直。心脏病变，强直性脊柱炎的危害不仅体现在对患者情绪的影响，还会造成患者的心脏病变。以主动脉瓣病变较为常见，据尸检发同约25%的强直性脊柱炎病例中，有主动脉根部病变，心脏受累在临床上可无症状，亦可有明显表现。
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我们大家都知道，不管是对于任何一种疾病，只有做到早发现，早治疗，把握最佳的治疗时间才能够将这种疾病所带来的危害降到最低，从而让自己尽快的恢复健康的人生，对于强直性脊柱炎这种疾病也不例外，那么强直性脊柱炎疾病的危害有哪些?
\n强直性脊柱炎疾病的危害有哪些?主要有以下几点：
\n1、累及髋关节是强直性脊柱炎的危害之一，造成股骨头内纤维组织大量增生，导致关节软骨面受到长期的压力，软骨营养障碍而发生破坏、变薄，最后消失。
\n2、强直性脊柱炎患者普遍都伴有骨质疏松，以椎体改变比较明显，并且多伴有骨质增生、韧带骨化和骨关节硬化等，一般常常是骨质增生和骨质疏松同时并存，以脊柱各椎体表现最为明显。强直性脊柱炎晚期有少数患者马尾神经受损出现慢性进行性马尾神经综合征。
\n3、眼损害也是患上强直性脊柱炎疾病的危害之一，是最常见的关节外表现，以急性葡萄膜炎和急性虹膜炎多见，也可发生急性结膜炎，如治疗不当或延误治疗，也可发生视力障碍。
\n4、强直性脊柱炎也会导致肩关节强直。肩关节活动受限主要来源于肿胀，它会影响患者梳头、抬手等日常活动。
\n5、强直性脊柱炎对髋关节的影响是最为普遍的。临床调查发现：髋关节强直的患者共占强直性脊柱炎中晚期的60%以上。髋部疼痛剧烈，其部分表现为臀部、腹股沟部位、大腿内侧部位疼痛，继续发展髋关节活动功能受限，髋关节周围肌肉萎缩，最后髋关节出现骨性强直。
\n6、强直性脊柱炎的危害不仅体现在对患者情绪的影响，还会造成患者的心脏病变。以主动脉瓣病变较为常见，据尸检发同约25%的强直性脊柱炎病例中，有主动脉根部病变，心脏受累在临床上可无症状，亦可有明显表现。
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强直性脊柱炎是很常见的一个疾病，很多患者会表现出来严重的腰背部疼痛，甚至也会觉得有一些僵硬感，脊柱活动起来也会有一些受限的情况，一旦发作起来就需要考虑一些具体的问题，比如强直性脊柱炎会不会给患者带去严重的危害呢？
\n强直性脊柱炎发作危害有什么危害呢?
\n生活质量方面：强直性脊柱炎严重影响人们的生活质量，如不及时治疗，达到一定程度时则会造成残疾，强直性脊柱炎影响了患者生活的各各方面。强直性脊柱炎不仅影响了自已的生活，而且还影响了自已的家人，患有强直性脊柱炎的人，在生活上比较难以自理，如果不及时冶疗还会造成严重的残疾，而且在夫妻方面还会受到影响，强直性脊柱炎患者由于脊柱、关节畸形的发生，会对性生活造成一定的影响。
\n在生育方面：由于强直性脊柱炎具有一定的家族遗传性，对生育也会造成一定的影响。但由于强直性脊柱炎是多种病因所致的疾病，遗传只是其中的一个病因，并不是影响本病的惟一因素。也就是说强直性脊柱炎病人对下一代小孩子遗传可能性只有15%——25%之间。患者如果想要小孩，最好在提前半年或更长时间停用对小孩有害的药物。
\n在妇女分娩方面：由于强直性脊柱炎的耻骨联合多数出现侵蚀性软骨炎性病理改变，强直性脊柱炎初期耻骨联合关节软骨炎性坏死，坏死骨组织吸收， 强直性脊柱炎晚期骶髂关节融合，耻骨联合融合，这样会造成妇女分娩时骨盆骨缝无法打开，分娩困难，产生严重的影响。
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