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style=\"text-indent:32px;text-autospace:ideograph-numeric;text-align:justify;text-justify:inter-ideograph;line-height:200%\"><span style=\";font-family:宋体;line-height:200%;font-size:16px\"><span style=\"font-family:宋体\">大部分胶质瘤患者很关心的一个问题就是胶质瘤的检查都有哪些？第一个要做的是头颅</span>CT，可以初步判断是否有颅内占位。如果有胶质瘤的话，在CT表现为脑部低信号病变，低级别胶质瘤一般看不到病灶周围水肿，高级别胶质瘤常会伴有病灶周围水肿，CT还可以发现有无出血钙化，肿瘤伴有钙化的，肿瘤的病理类型为少枝可能性大，表现为高信号提示肿瘤的恶性程度比较高。除了头部CT外，需要做个核磁共振，在显示肿瘤的部位、性质等方面要优于CT检查。低级别胶质瘤在核磁共振上表现为T1低信号、T2高信号，白质表现，与周围的脑部正常组织在影像上较为清晰的边界，肿瘤周围水肿不明显表现，病变不强化。而高级别胶质瘤一般信号会不均，T1低信号、T2高信号，有出血的话T1也可能出现高信号，肿瘤与周围脑组织边界不清，水肿严重。还有可能做其他一些检查，比如正电子发射断层扫描、磁共振波谱等检查，进一步了解病变的糖代谢及其他分子代谢情况，从而进行鉴别诊断。</span></p><p style=\"text-indent:32px;text-autospace:ideograph-numeric;text-align:justify;text-justify:inter-ideograph;line-height:200%\"><span style=\";font-family:宋体;line-height:200%;font-size:16px\"><span style=\"font-family:宋体\">还会有些病变，比如脑炎，缺血等跟胶质瘤影像上会非常相似，不是很容易区分，最终的确诊还是需要病理诊断。胶质瘤患者首先是通过这些检查，对胶质瘤的部位以及恶性程度进行一个初步的临床判断，大致给一个等级，性质，然后决定手术后，病理诊断的结果为准。</span></span></p><p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px; color: rgb(46, 46, 46); font-family: &quot;Microsoft YaHei&quot;; font-size: 14px; white-space: normal; text-align: center;\"><img src=\"http://01luntan.com/ly_img/uimgs/1539830466814.png\" title=\"胶质瘤的检查有哪些\" alt=\"胶质瘤的检查有哪些\" width=\"600\" height=\"372\"/></p><p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px; color: rgb(46, 46, 46); font-family: &quot;Microsoft YaHei&quot;; font-size: 14px; white-space: normal; text-indent: 32px; text-align: justify; line-height: 28px;\"><span style=\"letter-spacing: 0px; margin: 0px; padding: 0px; font-family: 宋体; line-height: 32px; font-size: 16px;\"><span style=\"letter-spacing: 0px; margin: 0px; padding: 0px;\">上图是解放军总医院第一附属医院傅相平写的《脑胶质瘤解密》，希望能帮到更多的患者，同时胶质瘤解密总群成立，傅相平教授也会定期在群里为大家免费解答疑惑，患者或者患者家属也可以在群里互相讨论，全程不收取任何费用哦。</span></span></p><p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px; color: rgb(46, 46, 46); font-family: &quot;Microsoft YaHei&quot;; font-size: 14px; white-space: normal; text-align: center;\"><img src=\"http://01luntan.com/ly_img/uimgs/1539829777762.jpg\" title=\"胶质瘤的检查有哪些\" alt=\"胶质瘤的检查有哪些\" width=\"219\" height=\"300\"/></p>","barId":"1337","topicTypeId":null,"topicThemeId":"1036","readLevel":0,"files":"","clickNoLikeCount":0,"clickLikeCount":0,"clickCount":0,"score":0,"partCount":0,"replayCount":0,"publishStatus":0,"publishTime":0,"isCream":null,"canReply":0,"shareUrl":null,"foodCouponVal":0,"emailNotice":0,"permission":0,"zlyShare":0,"status":0,"sort":0,"highlight":0,"highlightEffectTime":0,"digest":0,"digestEffectTime":0,"top":0,"topEffectTime":0,"closed":0,"stamp":0,"icon":0,"bgcolor":null,"fontcolor":null,"favtimes":0,"isAdopt":0,"adoptId":null,"sortDate":0,"metaSearch":null,"rn":10},{"id":"24607","isDel":0,"createAt":0,"createBy":null,"createName":null,"updateAt":0,"updateBy":null,"updateName":null,"userId":null,"title":"胶质瘤吃什么食物好","content":"<p style=\";margin-bottom:0;line-height:200%\"><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　目前对胶质瘤医学上还缺乏有效的根治手段，术后患者身体虚弱要补充营养，对患者不能一概而论，要注意饮食不慎或忌口不严导致病情复发。患者能吃什么?不能吃什么?这是患者及家属非常关心的问题之一，要因人、因地、因时而异，要辨病、辨证而定。</span></p><p style=\";margin-bottom:0;line-height:200%\"><strong><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　一、胶质瘤患者需常吃的五种食物</span></strong></p><p style=\";margin-bottom:0;line-height:200%\"><strong><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　1、芦笋</span></strong></p><p style=\";margin-bottom:0;line-height:200%\"><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　芦笋是一种抗癌很好的食物，据北京三博脑科医院江涛教授称，芦笋具有调节机体代谢，提高身体免疫力的功效，在对高血压、心脏病、白血病、血癌、胶质瘤、等的预防和治疗中，具有很强的抑制作用和药理效应。</span></p><p style=\"margin-bottom: 0px; line-height: 200%; text-align: center;\"><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\"><img src=\"http://01luntan.com/ly_img/uimgs/1548125323222.jpg\" title=\"胶质瘤吃芦笋的好处\" alt=\"胶质瘤吃芦笋的好处\" width=\"555\" height=\"339\"/></span></p><p style=\";margin-bottom:0;line-height:200%\"><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　芦笋嫩茎中含有丰富的蛋白质、维生素、矿物质和人体所需的微量元素等，另外芦笋中含有特有的天门冬酰胺，及多种甾体皂甙物质，对心血管病、水肿、膀胱炎、白血病均有疗效，也有抗癌的效果，因此长期食用芦笋有益脾胃，对人体许多疾病有很好的治疗效果。</span></p><p style=\";margin-bottom:0;line-height:200%\"><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　同时芦笋所含多种维生素和微量元素的质量优于普通蔬菜。营养学家和素食界人士均认为它是健康食品和全面的抗癌食品。对其它癌症、胶质瘤等，也有很好效果。国际癌症病友协会研究认为，芦笋可以使细胞生长正常化，具有防止癌细胞扩散的功能。</span></p><p style=\";margin-bottom:0;line-height:200%\"><strong><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　2、薏米</span></strong></p><p style=\";margin-bottom:0;line-height:200%\"><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　最新的医学数据显示，薏米一种抗癌药物，初步鉴定，它对癌症的抑制率可达35％以上，尤其对于大脑疾病。薏米还是补身药用佳品。据最新的医药部门化验分析，薏米含丰富的蛋白质、脂肪、糖类。与猪脚、排骨和鸡一起炖，是一种滋补食品。夏天可以用薏米做“冷饮”是很好的消暑健身的清补剂。薏米的种仁和根又能入药治病。</span></p><p style=\"margin-bottom: 0px; line-height: 200%; text-align: center;\"><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\"><img src=\"http://01luntan.com/ly_img/uimgs/1548125424132.jpg\" title=\"胶质瘤吃薏米的好处\" alt=\"胶质瘤吃薏米的好处\" width=\"500\" height=\"314\"/></span></p><p style=\";margin-bottom:0;line-height:200%\"><strong><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　3、膳食食物</span></strong></p><p style=\";margin-bottom:0;line-height:200%\"><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　“膳食”纤维 主要包含哪些食物，糙米和胚牙精米，以及玉米、小米、大麦、小麦皮(米糠)和麦粉(黑面包的材料)等 膳食纤维之粗粮杂粮杂粮;此外，根菜类和海藻类中食物纤维较多，如牛蒡、胡萝卜、四季豆、红豆、豌豆、薯类和裙带菜等。膳食纤维是植物性成分，植物性食物是膳食纤维的天然食物来源。膳食纤维在蔬菜水果、粗粮杂粮、豆类及菌藻类食物中含量丰富。</span></p><p style=\";margin-bottom:0;line-height:200%\"><strong><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　4、海蜇</span></strong></p><p style=\";margin-bottom:0;line-height:200%\"><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　海蜇的味道甘、咸，性平。能清热化痰，消积，润肠，降血压。 海蜇含蛋白质、脂肪、维生素B1.B2和烟酸、钙、磷、铁、碘、胆碱等成分。经调查显示，静脉注射海蜇制剂能降低家兔血压。又可使兔的耳廓体表血管及蛙的周身血管舒张。</span></p><p style=\"margin-bottom: 0px; line-height: 200%; text-align: center;\"><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\"><img src=\"http://01luntan.com/ly_img/uimgs/1548125428525.jpg\" title=\"胶质瘤吃海蜇的好处\" alt=\"胶质瘤吃海蜇的好处\" width=\"613\" height=\"439\"/></span></p><p style=\";margin-bottom:0;line-height:200%\"><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　海蜇味道甘、咸，但是具有清热、润肠、降血压的功效，因为海蜇具有丰富的蛋白质、脂肪、钙、磷、铁、碘、胆碱等成分。能有效降低血压，缓解头昏头胀，是胶质瘤患者最佳的选择食物。</span></p><p style=\";margin-bottom:0;line-height:200%\"><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　胶质瘤患者常见的症状就是颅内压高，引发头疼，据调查显示，用海蜇煎液，以0.8～1.0毫升/公斤静脉注射于麻醉兔，可以降低血压，并使小肠容积增加(舒张血管)，肾容积缩小(可能由于肾缺血)。以此煎液灌注于兔耳血管及蛙全身血管后，亦有扩张血管的作用。临床上用雪羹汤(海蜇与荸荠合剂)治疗各期高血压，疗效满意及进步者达82.6％，可长期服用而无毒性与副作用，对早期患者更为适合。</span></p><p style=\";margin-bottom:0;line-height:200%\"><strong><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　5、炸蜈蚣</span></strong></p><p style=\";margin-bottom:0;line-height:200%\"><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　其实炸蜈蚣一种食品，将蜈蚣去毒油炸食用。经过现代技术处理后，含有丰富蛋白质，被称作抗脑瘤的食物之一。</span></p><p style=\";margin-bottom:0;line-height:200%\"><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　<strong>二、胶质瘤患者饮食禁忌</strong></span></p><p style=\";margin-bottom:0;line-height:200%\"><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　1、忌咖啡、可可等兴奋性饮料。</span></p><p style=\";margin-bottom:0;line-height:200%\"><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　2、忌辛辣刺激性食物，如葱、蒜、韭菜、花椒、辣椒、桂皮等。</span></p><p style=\";margin-bottom:0;line-height:200%\"><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　3、忌发霉、烧焦食物，如霉花生、霉黄豆、烧焦鱼肉。</span></p><p style=\";margin-bottom:0;line-height:200%\"><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　4、忌油腻、腌腊鱼肉、油煎、烟熏食物。</span></p><p style=\";margin-bottom:0;line-height:200%\"><span style=\"font-size:14px;line-height:200%;font-family:宋体;color:#2E2E2E\">　　5、忌过咸食物。</span></p><p><br/></p>","barId":"1337","topicTypeId":null,"topicThemeId":"1035","readLevel":0,"files":"","clickNoLikeCount":0,"clickLikeCount":0,"clickCount":0,"score":0,"partCount":0,"replayCount":0,"publishStatus":0,"publishTime":0,"isCream":null,"canReply":0,"shareUrl":null,"foodCouponVal":0,"emailNotice":0,"permission":0,"zlyShare":0,"status":0,"sort":0,"highlight":0,"highlightEffectTime":0,"digest":1,"digestEffectTime":0,"top":0,"topEffectTime":0,"closed":0,"stamp":0,"icon":0,"bgcolor":null,"fontcolor":null,"favtimes":0,"isAdopt":0,"adoptId":null,"sortDate":0,"metaSearch":null,"rn":8},{"id":"22614","isDel":0,"createAt":0,"createBy":null,"createName":null,"updateAt":0,"updateBy":null,"updateName":null,"userId":null,"title":"胶质瘤手术后发烧怎么处理","content":"<p style=\"text-indent:32px;text-autospace:ideograph-numeric;text-align:justify;text-justify:inter-ideograph;line-height:200%\"><span style=\";font-family:宋体;line-height:200%;font-size:16px\"><span style=\"font-family:宋体\">胶质瘤手术后发烧也是一个比较常见的症状，那该怎么去处理呢？也是大部分患者以及家属很关心地问题。因为患者会在开颅手术后身体非常虚弱，身体抵抗力会有所下降，抵抗外界的入侵显得微不足道，很容易产生发烧症状，这时候是非常需要患者家属对其进行很好的护理工作的，比如说做些有营养的食物给患者吃，患者平时喜欢吃的，可口的食物，这样身体会慢慢恢复过来。如果是高烧不退，可以先进行一定的物理降温，必要时找医生给患者进行药物控制，这样使患者能舒服点，调整好心态，好好吃饭多休息，也是会慢慢恢复过来的，患者和家属一定不能着急！还有一种情况是颅内感染，这样会比较麻烦点，这时一定要联系医生，说明情况，通过治疗来进行控制缓解，一般在一周左右就会得到有效改善，如果比较严重的是需要考虑再次开颅进行处理。</span></span></p><p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px; color: rgb(46, 46, 46); font-family: &quot;Microsoft YaHei&quot;; font-size: 14px; white-space: normal; text-align: center;\"><img src=\"http://01luntan.com/ly_img/uimgs/1539830466814.png\" title=\"胶质瘤手术后发烧怎么处理\" alt=\"胶质瘤手术后发烧怎么处理\" width=\"600\" height=\"372\"/></p><p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px; color: rgb(46, 46, 46); font-family: &quot;Microsoft YaHei&quot;; font-size: 14px; white-space: normal; text-indent: 32px; text-align: justify; line-height: 28px;\"><span style=\"letter-spacing: 0px; margin: 0px; padding: 0px; font-family: 宋体; line-height: 32px; font-size: 16px;\"><span style=\"letter-spacing: 0px; margin: 0px; padding: 0px;\">上图是解放军总医院第一附属医院傅相平写的《脑胶质瘤解密》，希望能帮到更多的患者，同时胶质瘤解密总群成立，傅相平教授也会定期在群里为大家免费解答疑惑，患者或者患者家属也可以在群里互相讨论，全程不收取任何费用哦。</span></span></p><p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px; color: rgb(46, 46, 46); font-family: &quot;Microsoft YaHei&quot;; font-size: 14px; white-space: normal; text-align: center;\"><img src=\"http://01luntan.com/ly_img/uimgs/1539829777762.jpg\" title=\"胶质瘤手术后发烧怎么处理\" alt=\"胶质瘤手术后发烧怎么处理\" width=\"219\" height=\"300\"/></p>","barId":"1337","topicTypeId":null,"topicThemeId":"1034","readLevel":0,"files":"","clickNoLikeCount":0,"clickLikeCount":0,"clickCount":0,"score":0,"partCount":0,"replayCount":0,"publishStatus":0,"publishTime":0,"isCream":null,"canReply":0,"shareUrl":null,"foodCouponVal":0,"emailNotice":0,"permission":0,"zlyShare":0,"status":0,"sort":0,"highlight":0,"highlightEffectTime":0,"digest":0,"digestEffectTime":0,"top":0,"topEffectTime":0,"closed":0,"stamp":0,"icon":0,"bgcolor":null,"fontcolor":null,"favtimes":0,"isAdopt":0,"adoptId":null,"sortDate":0,"metaSearch":null,"rn":6},{"id":"14918","isDel":0,"createAt":0,"createBy":null,"createName":null,"updateAt":0,"updateBy":null,"updateName":null,"userId":null,"title":"脑胶质瘤四级刚做完手术后面该怎么","content":"<p>脑胶质瘤四级刚做完手术后面该怎么，求专家解答一下 我该怎么办</p>","barId":"1337","topicTypeId":null,"topicThemeId":"1033","readLevel":0,"files":"","clickNoLikeCount":0,"clickLikeCount":0,"clickCount":0,"score":0,"partCount":0,"replayCount":0,"publishStatus":0,"publishTime":0,"isCream":null,"canReply":0,"shareUrl":null,"foodCouponVal":0,"emailNotice":0,"permission":0,"zlyShare":0,"status":0,"sort":0,"highlight":0,"highlightEffectTime":0,"digest":0,"digestEffectTime":0,"top":0,"topEffectTime":0,"closed":0,"stamp":0,"icon":0,"bgcolor":null,"fontcolor":null,"favtimes":0,"isAdopt":0,"adoptId":null,"sortDate":0,"metaSearch":null,"rn":62},{"id":"25937","isDel":0,"createAt":0,"createBy":null,"createName":null,"updateAt":0,"updateBy":null,"updateName":null,"userId":null,"title":"1p19q非联合缺失好不好","content":"<p style=\"text-align:left;line-height:200%\"><span style=\"font-size:19px;line-height:200%;font-family:宋体\">1p19q</span><span style=\"font-size:19px;line-height:200%;font-family:宋体\">非联合缺失好不好</span>？懂的帮忙看下，现在医生只让放疗</p><p style=\"text-align: center;\"><img src=\"http://01luntan.com/ly_img/uimgs/1562509295044.png\" title=\"1p19q非联合缺失好不好\" alt=\"1p19q非联合缺失好不好\" width=\"599\" height=\"706\"/></p>","barId":"1337","topicTypeId":null,"topicThemeId":"1032","readLevel":0,"files":"","clickNoLikeCount":0,"clickLikeCount":0,"clickCount":0,"score":0,"partCount":0,"replayCount":0,"publishStatus":0,"publishTime":0,"isCream":null,"canReply":0,"shareUrl":null,"foodCouponVal":0,"emailNotice":0,"permission":0,"zlyShare":0,"status":0,"sort":0,"highlight":0,"highlightEffectTime":0,"digest":0,"digestEffectTime":0,"top":0,"topEffectTime":0,"closed":0,"stamp":0,"icon":0,"bgcolor":null,"fontcolor":null,"favtimes":0,"isAdopt":0,"adoptId":null,"sortDate":0,"metaSearch":null,"rn":62},{"id":"1697","isDel":0,"createAt":0,"createBy":null,"createName":null,"updateAt":0,"updateBy":null,"updateName":null,"userId":null,"title":"胶质瘤有哪些典型症状","content":"<p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px;\">　　神经胶质瘤的病程依其病理类型和所在部位长短不一，自出现症状至就诊时间一般多为数周至数月，少数可达数年。恶性程度高的和后颅窝肿瘤病史多较短，较良性的肿瘤或位于所谓静区的肿瘤病史多较长。肿瘤如有出血或囊肿形成、症状发展进程可加快，有的甚至可类似脑血管病的发展过程。</p>\n<p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px;\">　　症状主要有两方面的表现。一是颅内压增高和其他一般症状，如头痛、呕吐、视力减退、复视、癫痫发作和精神症状等。另一是脑组织受肿瘤的压迫、浸润、破坏所产生的局部症状，造成神经功能缺失。</p>\n<p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px;\">　　<strong>头痛</strong>大多由于颅内压增高所致，肿瘤增长颅内压逐渐增高，压迫、牵扯颅内疼痛敏感结构如血管、硬膜和某些颅神经而产生头痛。大多为跳痛、胀痛，部位多在额颞部或枕部，一侧大脑半球浅在的肿瘤，头痛可主要在患侧、头痛开始为间歇性，多发生于清晨、随着肿瘤的发展，头痛逐渐加重，持续时间延长。</p>\n<p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px;\">　　<strong>呕吐</strong>系由于延髓呕吐中枢或迷走神经受刺激所致，可先无恶心，是喷射性。在儿童可由于颅缝分离头痛不显着，且因后颅窝肿瘤多见，故呕吐较突出。</p>\n<p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px;\">　　<strong>颅内压增高</strong>可产生视乳头水肿，且久致视神经继发萎缩，视力下降。肿瘤压迫视神经者产生原发性视神经萎缩，亦致视力下降。外展神经易受压挤牵扯，常致麻痹，产生复视。</p>\n<p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px;\">　　一部分肿瘤病人有癫痫症状，并可为早期症状。癫痫始于成年后者一般为症状性，大多为脑瘤所致。药物不易控制或发作性质有改变者，都应考虑有脑瘤存在。肿瘤邻近皮层者易发生癫痫，深在者则少见。局限性癫痫有定位意义。</p>\n<p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px;\">　　有些肿瘤特别是位于额叶者可逐渐出现精神症状，如性格改变、淡漠、言语及活动减少，注意力不集中，记忆力减退，对事物不关心，不知整洁等。</p>\n<p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px;\">　　局部症状则依肿瘤所在部位产生相应的症状，进行性加重。特别是恶性胶质瘤，生长较快，对脑组织浸润破坏，周围脑水肿亦显着，局部症状较明显，发展亦快。在脑室内肿瘤或位于静区的肿瘤早期可无局部症状。而在脑干等重要功能部位的肿瘤早期即出现局部症状，经过相当长时间才出现颅内压增高症状。某些发展较慢的肿瘤，由于代偿作用，亦常至晚期才出现颅内压增高症状。</p>\n<p>&nbsp;</p>","barId":"1337","topicTypeId":null,"topicThemeId":"1029","readLevel":0,"files":"","clickNoLikeCount":0,"clickLikeCount":0,"clickCount":0,"score":0,"partCount":0,"replayCount":0,"publishStatus":0,"publishTime":0,"isCream":null,"canReply":0,"shareUrl":null,"foodCouponVal":0,"emailNotice":0,"permission":0,"zlyShare":0,"status":0,"sort":0,"highlight":0,"highlightEffectTime":0,"digest":0,"digestEffectTime":0,"top":0,"topEffectTime":0,"closed":0,"stamp":0,"icon":0,"bgcolor":null,"fontcolor":null,"favtimes":0,"isAdopt":0,"adoptId":null,"sortDate":0,"metaSearch":null,"rn":4},{"id":"25054","isDel":0,"createAt":0,"createBy":null,"createName":null,"updateAt":0,"updateBy":null,"updateName":null,"userId":null,"title":"2020胶质瘤新药——让胶质瘤细胞自杀","content":"<p style=\"line-height:200%\"><span style=\"font-family:宋体\">对于胶质瘤这种疾病，新药的研究一直是科学家们努力的方向，那科学家们发现了一种新药可以治疗胶质瘤，那跟着我一起从下面来找一找究竟是什么吧。</span></p><p style=\"line-height:200%\">&nbsp;</p><p style=\"line-height:200%\"><span style=\"font-family:宋体\">研究人员表示，从患者身上提取出来的胶质瘤细胞因为接触到暴露的化学物质而自己灭亡了，这项研究可能是解决胶质母细胞瘤等癌症的第一步。这项由利兹大学领导的研究发现，名为</span>KHS101<span style=\"font-family:宋体\">的合成化学物质能够从胶质母细胞瘤中切除肿瘤细胞的能量来源，从而导致细胞死亡。</span></p><p style=\"line-height:200%\">&nbsp;</p><p style=\"line-height:200%\"><span style=\"font-family:宋体\">该研究发表在“科学转化医学”杂志上，这种疾病是最致命的癌症之一，</span>5<span style=\"font-family:宋体\">年生存率低于</span>5%<span style=\"font-family:宋体\">。英国每年有超过</span>2,000<span style=\"font-family:宋体\">人被诊断患有胶质母细胞瘤，最近在议会讨论了这种疾病，迫切需要改善治疗方案。</span></p><p style=\"line-height:200%\">&nbsp;</p><p style=\"line-height:200%\">&nbsp;<span style=\"font-family:宋体\">研究人员</span>Heiko Wurdak<span style=\"font-family:宋体\">博士说，当我们开始这项研究时，我们认为</span>KHS101<span style=\"font-family:宋体\">可能会减缓胶质母细胞瘤的生长，但我们惊讶地发现肿瘤细胞基本上是自杀了。这种化学物质破坏了肿瘤细胞内的线粒体和新陈代谢，并切断了能量供应，导致其自我毁灭。</span></p><p style=\"line-height:200%\">&nbsp;</p><p style=\"line-height:200%\"><span style=\"font-family:宋体\">为了测试</span>KHS101<span style=\"font-family:宋体\">是否可以穿过哺乳动物的血脑屏障，研究人员将肿瘤细胞从人体转移到小鼠体内。血脑屏障阻止大多数分子进入大脑并严重限制治疗选择。与给予安慰剂的小鼠相比，该化学物质成功穿过血脑屏障并显着限制了</span>KHS101<span style=\"font-family:宋体\">治疗的小鼠的肿瘤生长（约</span>50<span style=\"font-family:宋体\">％），而存活率增加。重要的是，正常脑细胞不受</span>KHS101<span style=\"font-family:宋体\">的影响。</span></p><p style=\"line-height:200%\">&nbsp;</p><p style=\"line-height:200%\"><span style=\"font-family:宋体\">对</span>KHS101<span style=\"font-family:宋体\">进一步研究，科学家可能会发现类似的药物——能够扰乱肿瘤细胞自我毁灭的能量来源，将为胶质母细胞瘤提供全新的治疗途径。</span></p><p style=\"line-height:200%\">&nbsp;</p><p style=\"line-height:200%\"><span style=\"font-family:宋体\">肿瘤新药的研究是医疗上很重要的一步，癌症的治疗是离不开药物的辅佐的，因此对于胶质瘤这种疾病来说也并不例外。科学家们找到一种新的药物，目的就是可以通过控制住疾病，从而可以延长患者的寿命，这就是科学家们的终极目的了。据研究者预估，这种新药大约于</span>2020<span style=\"font-family:宋体\">年上市。也是胶质瘤患者朋友的一个福音了。</span></p><p style=\"line-height: 200%; text-align: center;\">&nbsp;<img src=\"http://01luntan.com/ly_img/uimgs/1552788953417.jpg\" title=\"2020胶质瘤新药信息交流群\" alt=\"2020胶质瘤新药信息交流群\" width=\"250\" height=\"343\"/></p><p style=\"line-height: 200%; text-align: center;\"><span style=\"font-size:16px;line-height:200%;font-family:宋体\">欢迎扫描二维码加入</span><span style=\"font-size:16px;line-height:200%\">QQ</span><span style=\"font-size:16px;line-height:200%;font-family:宋体\">群，与病友共同交流治疗信息与心得</span></p><p><br/></p>","barId":"1337","topicTypeId":null,"topicThemeId":"1028","readLevel":0,"files":"","clickNoLikeCount":0,"clickLikeCount":0,"clickCount":0,"score":0,"partCount":0,"replayCount":0,"publishStatus":0,"publishTime":0,"isCream":null,"canReply":0,"shareUrl":null,"foodCouponVal":0,"emailNotice":0,"permission":0,"zlyShare":0,"status":0,"sort":0,"highlight":0,"highlightEffectTime":0,"digest":0,"digestEffectTime":0,"top":0,"topEffectTime":0,"closed":0,"stamp":0,"icon":0,"bgcolor":null,"fontcolor":null,"favtimes":0,"isAdopt":0,"adoptId":null,"sortDate":0,"metaSearch":null,"rn":63},{"id":"14444","isDel":0,"createAt":0,"createBy":null,"createName":null,"updateAt":0,"updateBy":null,"updateName":null,"userId":null,"title":"大脑胶质瘤","content":"<p style=\"margin: 0px; padding: 0pt; text-align: left; line-height: 200%; text-indent: 24pt;\"><span style=\"margin: 0px; color: rgb(46, 46, 46); text-transform: none; letter-spacing: 0pt; font-family: 宋体; font-size: 12pt; font-style: normal; font-weight: normal;\"><span style=\"font-family:宋体\">什么是大脑胶质瘤呢？<span style=\"display: inline !important; float: none; background-color: transparent; color: rgb(46, 46, 46); font-family: 宋体; font-size: 16px; font-style: normal; font-variant: normal; font-weight: 400; letter-spacing: 0px; orphans: 2; text-align: left; text-decoration: none; text-indent: 32px; text-transform: none; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;\">大脑胶质瘤就是脑胶质瘤。</span></span></span></p><p style=\"margin: 0px; padding: 0pt; text-align: left; line-height: 200%; text-indent: 24pt;\"><span style=\"margin: 0px; color: rgb(46, 46, 46); text-transform: none; letter-spacing: 0pt; font-family: 宋体; font-size: 12pt; font-style: normal; font-weight: normal;\"><span style=\"font-family:宋体\">它的定义是</span></span><span style=\"margin: 0px; color: rgb(46, 46, 46); text-transform: none; letter-spacing: 0pt; font-family: 宋体; font-size: 12pt; font-style: normal; font-weight: normal;\"><span style=\"font-family:宋体\">源自神经上皮的肿瘤统称为脑胶质瘤，占颅脑肿瘤的</span>40%~50%，是最常见的颅内恶性肿瘤</span><span style=\"margin: 0px; color: rgb(46, 46, 46); text-transform: none; letter-spacing: 0pt; font-family: 宋体; font-size: 12pt; font-style: normal; font-weight: normal;\"><span style=\"font-family:宋体\">以及</span></span><span style=\"margin: 0px; color: rgb(46, 46, 46); text-transform: none; letter-spacing: 0pt; font-family: 宋体; font-size: 12pt; font-style: normal; font-weight: normal;\"><span style=\"font-family:宋体\">原发性中枢神经系统肿瘤。在原发性脑瘤中，胶质瘤由于治疗难度大，致残、致死率极高，被称为癌后。</span></span><span style=\"margin: 0px; color: rgb(46, 46, 46); text-transform: none; letter-spacing: 0pt; font-family: 宋体; font-size: 12pt; font-style: normal; font-weight: normal;\"></span></p><p style=\"margin: 0px; padding: 0pt; text-align: left; line-height: 200%; text-indent: 24pt;\"><span style=\"margin: 0px; color: rgb(46, 46, 46); text-transform: none; letter-spacing: 0pt; font-family: 宋体; font-size: 12pt; font-style: normal; font-weight: normal;\"><span style=\"font-family:宋体\">其</span></span><span style=\"margin: 0px; color: rgb(46, 46, 46); text-transform: none; letter-spacing: 0pt; font-family: 宋体; font-size: 12pt; font-style: normal; font-weight: normal;\"><span style=\"font-family:宋体\">具</span></span><span style=\"margin: 0px; color: rgb(46, 46, 46); text-transform: none; letter-spacing: 0pt; font-family: 宋体; font-size: 12pt; font-style: normal; font-weight: normal;\"><span style=\"font-family:宋体\">体的致病因素现在是不明确的，也是没有定论的，多数学者认为它是由多种因素综合作</span></span><span style=\"margin: 0px; color: rgb(46, 46, 46); text-transform: none; letter-spacing: 0pt; font-family: 宋体; font-size: 12pt; font-style: normal; font-weight: normal;\"><span style=\"font-family:宋体\">用的结果。包括先天的遗传高危因素环境的致癌因素以及相互作用所导致的结果。最基本的致病原因还是基因的突变，由于基因的突变导致胶质瘤的发生和发展。</span></span></p><p style=\"margin: 0px; padding: 0pt; text-align: left; line-height: 200%; text-indent: 24pt;\"><span style=\"margin: 0px; color: rgb(46, 46, 46); text-transform: none; letter-spacing: 0pt; font-family: 宋体; font-size: 12pt; font-style: normal; font-weight: normal;\"><span style=\"font-family:宋体\"><img width=\"600\" height=\"325\" title=\"大脑胶质瘤\" alt=\"大脑胶质瘤\" src=\"http://01luntan.com/ly_img/uimgs/1530235894287.jpg\"/></span></span></p><p style=\"margin: 0px; padding: 0pt; text-align: left; line-height: 200%; text-indent: 24pt;\"><span style=\"margin: 0px; color: rgb(46, 46, 46); text-transform: none; letter-spacing: 0pt; font-family: 宋体; font-size: 12pt; font-style: normal; font-weight: normal;\"><span style=\"font-family:宋体\"></span></span><span style=\"margin: 0px; color: rgb(46, 46, 46); text-transform: none; letter-spacing: 0pt; font-family: 宋体; font-size: 12pt; font-style: normal; font-weight: normal;\"><span style=\"font-family:宋体\"><span style=\"display: inline !important; float: none; background-color: transparent; color: rgb(46, 46, 46); font-family: 宋体; font-size: 16px; font-style: normal; font-variant: normal; font-weight: 400; letter-spacing: 0px; line-height: 32px; orphans: 2; text-align: left; text-decoration: none; text-indent: 32px; text-transform: none; -webkit-text-stroke-width: 0px; word-spacing: 0px;\">找良医网温馨提示：如有身体不适，请及时就医！</span></span></span></p><span style=\"margin: 0px; color: rgb(46, 46, 46); text-transform: none; letter-spacing: 0pt; font-family: 宋体; font-size: 12pt; font-style: normal; font-weight: normal;\"></span><p><br/></p>","barId":"1337","topicTypeId":null,"topicThemeId":"1026","readLevel":0,"files":"","clickNoLikeCount":0,"clickLikeCount":0,"clickCount":0,"score":0,"partCount":0,"replayCount":0,"publishStatus":0,"publishTime":0,"isCream":null,"canReply":0,"shareUrl":null,"foodCouponVal":0,"emailNotice":0,"permission":0,"zlyShare":0,"status":0,"sort":0,"highlight":0,"highlightEffectTime":0,"digest":0,"digestEffectTime":0,"top":0,"topEffectTime":0,"closed":0,"stamp":0,"icon":0,"bgcolor":null,"fontcolor":null,"favtimes":0,"isAdopt":0,"adoptId":null,"sortDate":0,"metaSearch":null,"rn":11}],"pageObj":{"list":[{"id":"24e7728c848511e9972100163e0462f1","isDel":0,"createAt":1559404299607,"createBy":"84404015eff611e6a61c00163e04584d","createName":"13911686944","updateAt":0,"updateBy":null,"updateName":null,"userId":"84404015eff611e6a61c00163e04584d","targetUserId":null,"topicId":"24957","replyPid":null,"reply":"<p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px; color: rgb(46, 46, 46); font-family: &quot;Microsoft YaHei&quot;; font-size: 14px; white-space: normal; text-align: center;\"><img src=\"http://01luntan.com/ly_img/uimgs/1554739907474.png\" title=\"国际治疗胶质瘤最新治疗方法\" alt=\"国际治疗胶质瘤最新治疗方法\" width=\"150\" height=\"150\"/></p><p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px; color: rgb(46, 46, 46); font-family: &quot;Microsoft YaHei&quot;; font-size: 14px; white-space: normal;\"><br/></p><p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px; color: rgb(46, 46, 46); font-family: &quot;Microsoft YaHei&quot;; font-size: 14px; white-space: normal; text-align: center;\"><span style=\"letter-spacing: 0px; margin: 0px; padding: 0px; font-family: 宋体; font-size: 19px;\">下载二维码微信识别，观看傅相平教授主讲《脑胶质瘤解密》，看完对这个病就完全明白了</span></p><p><br/></p>","floor":1,"isAdopt":0,"type":0}],"list4Map":null,"pageBegin":0,"pageSize":5,"pageNumber":1,"totalPage":1,"totalRow":1},"loginUser":null,"replies":[{"id":"24e7728c848511e9972100163e0462f1","isDel":0,"createAt":1559404299607,"createBy":"84404015eff611e6a61c00163e04584d","createName":"13911686944","updateAt":0,"updateBy":null,"updateName":null,"userId":"84404015eff611e6a61c00163e04584d","targetUserId":null,"topicId":"24957","replyPid":null,"reply":"<p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px; color: rgb(46, 46, 46); font-family: &quot;Microsoft YaHei&quot;; font-size: 14px; white-space: normal; text-align: center;\"><img src=\"http://01luntan.com/ly_img/uimgs/1554739907474.png\" title=\"国际治疗胶质瘤最新治疗方法\" alt=\"国际治疗胶质瘤最新治疗方法\" width=\"150\" height=\"150\"/></p><p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px; color: rgb(46, 46, 46); font-family: &quot;Microsoft YaHei&quot;; font-size: 14px; white-space: normal;\"><br/></p><p style=\"margin-top: 0px; margin-bottom: 0px; padding: 0px; color: rgb(46, 46, 46); font-family: &quot;Microsoft YaHei&quot;; font-size: 14px; white-space: normal; text-align: center;\"><span style=\"letter-spacing: 0px; margin: 0px; padding: 0px; font-family: 宋体; font-size: 19px;\">下载二维码微信识别，观看傅相平教授主讲《脑胶质瘤解密》，看完对这个病就完全明白了</span></p><p><br/></p>","floor":1,"isAdopt":0,"type":0,"nickNameHead":null,"targetHead":null,"username":null,"nickName":null,"nickNameId":null,"targetNickName":null,"targetId":null,"targetUsername":null,"topicTitle":null,"forumUser":{"id":"84404015eff611e6a61c00163e04584d","isDel":0,"createAt":1486775274108,"createBy":null,"createName":null,"updateAt":0,"updateBy":null,"updateName":null,"username":"13911686944","password":"000000","level":0,"nickName":"赵金亮","realName":null,"signName":"c","head":null,"phone":"13911686944","mobile":null,"wechat":null,"qq":null,"email":null,"address":null,"identityType":6,"userType":2,"isPhoneBind":1,"status":0,"accountSource":0,"isStrangerMsg":0,"departmentId":null,"departmentName":null,"sex":1,"provinceId":"110000","cityId":"","userLevel":0,"modifyNameCount":1},"forumUserActiveInfo":{"id":"fd502687f19a11e6a61c00163e04584d","isDel":0,"createAt":1486955865846,"createBy":"84404015eff611e6a61c00163e04584d","createName":"13911686944","updateAt":1588636711945,"updateBy":"84404015eff611e6a61c00163e04584d","updateName":"13911686944","userId":"84404015eff611e6a61c00163e04584d","topicCount":1669,"replayCount":744,"favorteCount":0,"beFavorteCount":0,"creamCount":229,"focusCount":2,"fansCount":2,"integralCount":3316,"foodCouponCount":9360,"lastLoginTime":0,"lastLoginIp":null,"downloadCount":0,"uploadCount":0},"forumUserIdentificateDto":{"id":"b24baed2f19b11e6a61c00163e04584d","isDel":0,"createAt":1486956169485,"createBy":"84404015eff611e6a61c00163e04584d","createName":"13911686944","updateAt":0,"updateBy":null,"updateName":null,"userId":"84404015eff611e6a61c00163e04584d","realName":"hng ","certifiedStatus":2,"phone":"13911686944","email":"hgfhgf@qq.com","hospitalId":"14654","departmentId":"2085","illName":"良性阵发性位置性眩晕","illId":"d3249cd6a90711e7a3d800163e04584d","cardType":1,"cardImg":"http://01luntan.com/ly_img/1532705618392.png","idCardImg":"","identityType":2,"stop":0,"departmentName":"耳鼻咽喉头颈外科","hospitalName":null},"forumUserFans":null,"lyClickLike":null,"likeClicks":0,"noLikeClicks":0,"checkcode":null,"replyPidReply":null}],"forumUserFans":null,"herfList":[],"only":"0","topic":{"id":"24957","isDel":0,"createAt":1551715181422,"createBy":"84404015eff611e6a61c00163e04584d","createName":"13911686944","updateAt":0,"updateBy":null,"updateName":null,"userId":"84404015eff611e6a61c00163e04584d","title":"国际治疗胶质瘤最新治疗方法","content":"<p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　近日，国际治疗胶质瘤治疗研究领域传来两个让人欣喜的前沿消息：</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\">　　<span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">1. </span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">杜克癌症研究所的研究人员发现了胶质母细胞瘤（</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">GBM</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">）患者中缺失的</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">T</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">细胞的踪迹，它们被大量的隔离在骨髓中，骨髓中</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">T</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">细胞的隔离是</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">T</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">细胞功能障碍的肿瘤适应性模式，其逆转或可成为一种有前途的免疫治疗辅助手段。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\">　　<span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">2. </span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">利兹大学领导的一项研究发现，合成的小分子</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">KHS101</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">能够从胶质母细胞瘤中切除肿瘤细胞的能量来源，从而导致肿瘤细胞死亡，或许有望在未来几年开发出一种对抗胶质母细胞瘤的新疗法。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><strong><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　脑胶质瘤简介</span></strong></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　脑胶质瘤是由于大脑和脊髓胶质细胞癌变所产生的，是最常见的原发性颅脑肿瘤。胶质瘤起源于外胚层，是神经系统最常见的原发性肿瘤，约占颅内原发性肿瘤的</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">50</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">％以上。其特点为生长迅速、侵袭性强、手术后易复发、病死率高。在所有新发肿瘤中，胶质瘤占</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">1.4</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">％，而死于胶质瘤的患者占所有肿瘤死亡患者的</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">2.4</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">％。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　总体来说，脑胶质瘤恶性度高、易复发、预后差，根治困难。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">&nbsp;</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><strong><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　治疗方式</span></strong></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　目前，关于脑胶质瘤主要有三种治疗方式：手术，放疗，化疗。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><strong><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　手术</span></strong></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　外科手术切除是脑瘤的主要治疗方式，特别是良性脑瘤。当脑瘤与重要的脑组织相连或者靠近时，外科医生只能尽量拿掉一部分，剩余部分需要依靠放疗和化疗才能消除。手术治疗前，医生或通过</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">CT</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">定位做穿刺病例穿刺，或者手术中取出组织做切片，判断病灶性质再决定后续如何治疗。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><strong><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　放疗</span></strong></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　放射治疗经常用于那些手术没有办法切除或者手术切除后残余的病灶，也可用于那些不可能接受手术治疗的病人。放疗的剂量和次数要根据不同的病理形态、部位、年龄而定，如果癌灶范围数量较小，可以做立体定位放疗，比如伽马刀。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><strong><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　化疗</span></strong></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　恶性脑瘤除了手术或者放疗等手段，还需要加上化疗，比如星状细胞瘤、脑胶质瘤、髓母细胞瘤等，临床常见的恶性脑瘤是其他癌症转移过来的，比如肺癌等，这种情况下，除了要治疗原发病灶还要治疗转移病灶，因此全身性的化疗对控制病情是有一定帮助的。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　替莫唑胺是治疗脑胶质瘤的化疗药物，可以显著延长患者的生存期，是目前效果较好的治疗手段。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　其他非主流或未普及推广的治疗方式不作讨论。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">&nbsp;</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><strong><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　治疗难点</span></strong></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　脑胶质瘤的治疗效果差强人意，一是因为血脑屏障的阻挡过滤原因，二是胶质瘤的特点所决定的。因此脑胶质瘤一直没有特别有效的治疗药物和方式，最近的两项研究进展给这个医学难题带来了喜讯。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">&nbsp;</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><strong><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　前沿信息</span></strong></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　逆转缺失免疫</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">T</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">细胞可对抗致命脑瘤</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　胶质母细胞瘤（</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">GBM</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">）会对人体免疫系统产生不寻常的影响，通常导致人体环境</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">T</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">细胞数量急剧下降，</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">T</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">细胞去向不明，因此很多激活</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">T</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">细胞的免疫疗法对脑胶质瘤无效。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　近期，杜克癌症研究所的研究人员追踪到了胶质母细胞瘤患者中缺失的</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">T</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">细胞</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">——</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">他们在骨髓中发现了大量的</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">T</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">细胞。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　在检查隐藏的</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">T</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">细胞时，研究小组发现</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">T</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">细胞表面缺少了一种叫做</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">S1P1</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">的受体，</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">S1P1</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">是使</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">T</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">细胞离开骨髓和淋巴系统的关键</span><span style=\"font-size: 16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">“</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">钥匙</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">”</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">。没有了</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">“</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">钥匙</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">”</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">，</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">T</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">细胞就被反锁在里面，无法传播和对抗感染，更不用说癌症了。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　为了弄清楚大脑是如何引发这种</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">S1P1</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">受体功能障碍的，研究小组做了进一步研究。目前的理论是，</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">S1P1</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">受体以某种方式接收到信号，从细胞表面缩回到细胞内部。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\">　　<span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">“</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">有趣的是，当我们在小鼠体内恢复</span><span style=\"font-size: 16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">T</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">细胞受体时，</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">T</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">细胞离开骨髓并进入肿瘤，所以我们知道这个过程是可逆的，</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">”</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">该课题负责人</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">Fecci</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">兴奋地说道。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\">　　<span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">Fecci</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">的团队正在与杜克大学的科学家</span><span style=\"font-size: 16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">RobertLefkowitz</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">（因发现</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">S1P1</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">所属受体类别获得</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">2012</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">年诺贝尔化学奖）合作，致力于开发能够恢复细胞表面受体的分子。</span></p><p style=\"line-height: 200%; background: rgb(246, 246, 246); text-align: center;\"><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">&nbsp;<img src=\"http://01luntan.com/ly_img/uimgs/1551715433239.png\" title=\"估计治疗胶质瘤最新治疗方法\" alt=\"估计治疗胶质瘤最新治疗方法\" width=\"700\" height=\"300\"/></span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><strong>　　</strong><strong><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">KHS101-</span></strong><strong><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">致命脑癌克星</span></strong></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　利兹大学的</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">Heiko Wurdak</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">博士领导了这个国际研究小组，他说</span><span style=\"font-size: 16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">:“</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">当我们开始这项研究时，我们认为</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">KHS101</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">可能会减缓胶质母细胞瘤的生长，但我们惊讶地发现，当癌细胞暴露在它面前时，基本上是自毁的。</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">”</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　具体来说，这种化学物质破坏了癌细胞内的线粒体和新陈代谢，切断了能量供应，导致了癌细胞自我毁灭。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　为了测试</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">KHS101</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">是否能穿过哺乳动物的血脑屏障（血脑屏障通常会阻止大部分分子进入大脑，严重限制了治疗的选择），研究人员将癌细胞从人类身上转移到老鼠体内。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　结果发现，与服用安慰剂的小鼠相比，</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">KHS101</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">成功地穿过了血脑屏障，显著降低了肿瘤生长</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">(</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">约</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">50%)</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">，从而提高了存活率。重要的是，正常的脑细胞不受这种化学物质的影响。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　研究小组还回顾了</span><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">KHS101</span><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">对肿瘤内细胞和不同患者肿瘤之间的不同基因图谱的有效性。过去，肿瘤的遗传变异使得确定治疗方法的工作变得复杂，但研究小组发现，所有经过检测的胶质母细胞瘤亚型细胞的变异都对现有治疗有反应。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">&nbsp;</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><strong><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　展望</span></strong></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　脑胶质瘤的治疗方法几十年来基本没有变化，因此迫切需要进行这样的临床前研究，以识别和鉴定潜在的新药。虽然这些发现令人鼓舞，但作为一种实验性的研究，在人类试验开始之前，需要进一步严格检测和改进，或许会发现更多的应用场景。</span></p><p style=\"line-height: 200%;background: rgb(246, 246, 246)\"><span style=\"font-size:16px;line-height:200%;font-family:宋体;color:#333333\">　　希望这些新发现可以提供更多治疗方法，让脑胶质瘤以及更多的肿瘤患者获益。</span></p><p style=\"line-height: 200%; background: rgb(246, 246, 246); text-align: center;\"><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\">&nbsp;<img src=\"http://01luntan.com/ly_img/uimgs/1551715847337.jpg\" title=\"1551715847337.jpg\" alt=\"????.jpg\"/></span></p><p style=\"line-height: 200%; background: rgb(246, 246, 246);\"><span style=\"font-size:16px;line-height:200%;font-family:&#39;Arial&#39;,&#39;sans-serif&#39;;color:#333333\"></span></p><p style=\"line-height: 200%; text-align: center;\"><span style=\"font-size:16px;line-height:200%;font-family:宋体\">欢迎扫描二维码加入</span><span style=\"font-size:16px;line-height:200%\">QQ</span><span style=\"font-size:16px;line-height:200%;font-family:宋体\">群，里面有专业医务人员帮病友们解答问题</span></p><p style=\"line-height: 200%; background: rgb(246, 246, 246);\"><span 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